What is Farxiga?
Farxiga (generic: dapagliflozin) is a sodium-glucose co-transporter 2 (SGLT2) inhibitor used to control blood sugar levels in adults with type 2 diabetes. The drug works by blocking the action of the SGLT2 protein, preventing the kidneys from reabsorbing glucose back into the bloodstream. Farxiga is made by AstraZeneca, and was approved by the U.S. Food & Drug Administration (FDA) on January 8, 2014.
How is Farxiga Taken?
Farxiga is a tablet taken once daily, in the morning, with or without food. The recommended starting dose of the drug is 5mg once daily.
Which Other Diabetes Drugs are SGLT2 Inhibitors?
In addition to Farxiga, other SGLT2 inhibitors include:
- Invokana (canagliflozin)
- Invokamet (canagliflozin and metformin)
- Glyxambi (empagliflozin and linagliptin)
- Jardiance (empagliflozin)
- Xigduo XR (dapagliflozin and metformin extended-release)
What’s the Problem?
Despite their short time on the market, SGLT2 inhibitor diabetes medications like Farxiga have been linked to an increased risk for a wide range of serious side effects including diabetic ketoacidosis (DKA), kidney failure, bone fractures and amputations of the foot, leg and toes.
Which Injuries are Lawsuits Being Filed Over?
Our lawyers are accepting potential lawsuits for people who developed the following injuries after taking Farxiga:
- Diabetic Ketoacidosis (DKA, Diabetic Acidosis, Metabolic Ketoacidosis, Metabolic Acidosis, Ketoacidosis)
- Kidney failure
- Amputations of the leg, foot or toes
Are There Other Side Effects?
Farxiga may also cause the following serious side effects in some users:
- Heart Attack (Myocardial Infarction or MI)
- Kidney Stones
- Bone Fractures / Bone Abnormalities
- Testicular Cancer
- Urinary Tract Infections (UTIs)
- Severe Dehydration / Fluid Imbalance
- Abnormal Weight Loss
- Hypersensitivity (Allergic Response)
- Blood Infections (Urosepsis)
- Fungal Infections
- Yeast Infections (both men and women)
- And more
What Should I Tell My Doctor Before Taking Farxiga?
If you understand the risks associated with Farxiga and are still considering taking the medication, be sure to disclose the following information to your physician before starting your regimen:
- All of your medical conditions, particularly those involving the kidneys, bladder or pancreas.
- If you’ve had diabetic ketoacidosis risk factors including type 1 diabetes, are eating less due to illness, surgery, or a change in your diet, are going to have surgery or binge drink.
- If you are pregnant or planning on becoming pregnant, as Farxiga may harm an unborn baby.
- If you are breastfeeding, or plan to breastfeed, since it is unknown whether Farxiga can pass into breast milk.
- All the medications you take, including prescription and nonprescription drugs, vitamins and herbal supplements.
Has the FDA Warned About Farxiga?
An FDA Drug Safety Communication issued on May 15, 2015, indicated that SGLT2 inhibitor diabetes drugs had been linked to at least 20 cases of diabetic ketoacidosis from March 2013 to June 6, 2014. The agency issued another safety communication about the SGLT2 inhibitor class on May 18, 2016, this time regarding an increased risk of foot, leg and toe amputations associated with canagliflozin (the active ingredient in Invokana).
FDA then issued an acute kidney injury warning on June 14, 2016, after receiving at least 101 confirmable reports of the condition in diabetes patients treated with SGLT2 inhibitors, some of which required emergency hospitalization and/or dialysis to treat.
What is Diabetic Ketoacidosis?
Ketoacidosis occurs when levels of blood acids called ketones are too high. If left untreated, the condition can lead to a diabetic coma or even death. Signs and symptoms may include:
- Difficulty breathing
- Abdominal pain
Has a Recall Been Issued?
Farxiga has only been on the U.S. market a short time (approved in January 2014), and no recall has yet been issued for it or any other SGLT2 inhibitor diabetes drug. The FDA issues recalls only after medications are found to be defective or potentially harmful. This often takes many years and adverse event reports from the public.
Is There a Class Action Lawsuit?
No class action has yet been filed alleging injuries from Farxiga. However, our law firm is reviewing potential individual lawsuits for former users of the drug who developed ketoacidosis, kidney damage, or required an amputation. If our lawyers find that you have a valid claim against the manufacturer, you may be eligible to receive compensation for medical expenses, lost wages, pain and suffering, and other damages.
Have There Been Any Settlements?
To date, there have been no significant settlements in the Farxiga litigation. Again, this is a new drug and the litigation is still in its early stages. However, with the large number of prescriptions written for the drug, as well as its potential health risks acknowledged by the FDA, our lawyers feel that enough lawsuits will be filed over Farxiga so that AstraZeneca will eventually decide to settle some or all of the cases.
What are Farxiga Lawsuits Alleging?
Complaints filed over diabetes drugs like Farxiga have alleged that manufacturers:
- Manufactured a dangerous or defective medication
- Failed to adequately warn the public and medical communities about risks of the medication
- Used illegal or improper marketing methods
- Hid or concealed knowledge of risks of the drug