Xigduo XR FAQ
What is Xigduo XR?
Xigduo XR contains dapagliflozin (Farxiga) and metformin (glucophage). The drug is used along with diet and exercise to improve blood sugar control in patients with type 2 diabetes when treatment with either dapagliflozin or metformin has not been effective. Xigduo XR is manufactured by AstraZeneca, and was approved by the U.S. Food & Drug Administration (FDA) in October 2014.
How Does it Work?
Dapagliflozin works by helping the kidneys excrete glucose from the blood. Metformin lowers glucose production in the liver and causes the intestines to absorb less glucose.
What is the Dosing?
Xigduo XR should be taken once daily in the morning with food, with gradual dose increase to reduce the risk of gastrointestinal effects due to metformin. The dose should be adjusted based on effectiveness and tolerability; not to exceed daily dose of dapagliflozin 10 mg and metformin 2000 mg (ie, 2 tablets of 5mg/1000mg).
How Much Does Xigduo Cost?
The cost for Xigduo XR oral tablet, extended release (5 mg-500 mg) is about $422 for a supply of 30 tablets, depending on the pharmacy you visit. Xigduo coupons are available to help reduce the cost.
Can Xigduo XR Help With Weight Loss?
Although Xigduo XR is not a weight loss or blood pressure medication, AstraZeneca claims that it may help people lose weight — on average 3% — and lower their systolic blood pressure. Individual results may vary.
What’s the Problem?
Lawsuits have been filed on behalf of former Xigduo XR users who were hospitalized due to diabetic ketoacidosis or kidney failure.
Which Side Effects has Xigduo XR Been Linked to?
- Diabetic Ketoacidosis (DKA, Diabetic Acidosis, Metabolic Ketoacidosis, Ketoacidosis)
- Heart Attack (Myocardial Infarction or MI)
- Amputations of the foot, leg or toes
- Kidney Failure (End Stage Renal Disease or “ESRD”)
- Kidney Cancer
- Kidney Infections (Pyelonephritis)
- Kidney Stones
- Bone Fractures
- Bone Abnormalities
- Testicular Cancer
- Urinary Tract Infections (UTIs)
- Bladder Cancer
- Severe Dehydration / Fluid Imbalance
- Abnormal Weight Loss
- Hypersensitivity (Allergic Response)
- Blood Infections (Urosepsis)
- Fungal Infections
- And more
What are Xigduo Lawsuits Alleging?
Xigduo XR Lawsuits allege that drugmaker AstraZeneca:
- Manufactured a defective or dangerous drug
- Failed to adequately warn about the risk of diabetic ketoacidosis and kidney damage with Xigduo XR
- Improperly marketed the drug
- Deliberately concealed knowledge regarding potential health risks of the medication
Which Injuries is your Firm Accepting?
Our lawyers are currently only accepting potential lawsuits on behalf of people who had diabetic ketoacidosis or kidney failure after taking Xigduo XR.
Has There Been a Recall?
Despite being linked to the above side effects, Xigduo XR has not been recalled in the U.S. or any other country. However, the drug has only been on the market a short time and the investigation into its potential health risks is still in its early stages. It often takes many years and thousands of hours of attorney time before all the facts leading to a recall emerge.
Is There a Class Action?
No class action has yet been filed in the Xigduo XR litigation. Instead, our lawyers are handling individual lawsuits for people who were injured by the drug. At some point, the complaints may be centralized into a multidistrict litigation (MDL) for pretrial discovery and investigation, as well as a possible settlement. In an MDL, each complaint is separate, and clients are not required to settle their case as part of a class action group. Each client gets to make their own decision as to whether to take their case to trial or not.
Have There Been Any Settlements?
Xigduo XR settlements have not yet been paid to victims and the litigation is still ongoing. As more complaints continue to be filed, the expected settlement amounts will continue to increase. In order to be considered for a settlement, you should contact our lawyers immediately to learn more about your legal rights.